发明授权
US08309566B2 Pyrimidine-2-amine compounds and their use as inhibitors of JAK kinases
有权
嘧啶-2-胺化合物及其作为JAK激酶抑制剂的用途
- 专利标题： Pyrimidine-2-amine compounds and their use as inhibitors of JAK kinases
- 专利标题（中）： 嘧啶-2-胺化合物及其作为JAK激酶抑制剂的用途
-
申请号： US12371550申请日： 2009-02-13
-
公开(公告)号： US08309566B2公开(公告)日： 2012-11-13
- 发明人: Somasekhar Bhamidipati , Jeffrey Clough , Ankush Argade , Rajinder Singh , Vadim Markovtosov , Pingyu Ding , Jiaxin Yu , Andy Atuegbu , Hui Hong , Ihab Darwish , Sambaiah Thota
- 申请人： Somasekhar Bhamidipati , Jeffrey Clough , Ankush Argade , Rajinder Singh , Vadim Markovtosov , Pingyu Ding , Jiaxin Yu , Andy Atuegbu , Hui Hong , Ihab Darwish , Sambaiah Thota
- 申请人地址： US CA South San Francisco
- 专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Seed IP Law Group PLLC
- 代理商 Travis Young
- 主分类号： A61K31/505
- IPC分类号： A61K31/505 ; C07D239/02 ; C07D401/12
摘要：
This invention is directed to compounds of formula (I): where n, m, Y, R1, R2, R3, R4 and R5 are disclosed herein, as isolated stereoisomers or mixtures thereof, or as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising the compounds of formula (I); and methods of using the compounds and the pharmaceutical compositions in treating diseases or conditions associated with JAK2 activity.
公开/授权文献
信息查询
