Invention Grant
- Patent Title: 8-substituted benzoazepines as toll-like receptor modulators
- Patent Title (中): 8-取代苯并吖庚因作为toll样受体调节剂
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Application No.: US13414579Application Date: 2012-03-07
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Publication No.: US08304407B2Publication Date: 2012-11-06
- Inventor: George A. Doherty , Charles Todd Eary , Robert D. Groneberg , Zachary Jones
- Applicant: George A. Doherty , Charles Todd Eary , Robert D. Groneberg , Zachary Jones
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- Agency: Viksnins Harris & Padys
- Agent John R. Moore; Corey M. Williams
- Main IPC: A61P37/00
- IPC: A61P37/00 ; A61K31/55 ; C07D223/16 ; C07D403/10
Abstract:
Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in the treatment of autoimmunity, inflammation allergy, asthma, graft rejection, graft versus host disease, infection, sepsis, cancer and immunodeficiency.
Public/Granted literature
- US20120165317A1 8-SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS Public/Granted day:2012-06-28
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