A portable electronic device having one or more proximity sensors. The portable electronic device comprises a housing, one or more signal emitters to direct source signal(s) based on the orientation of the housing, and one or more signal receivers to receive return signals corresponding to the source signal(s). For one embodiment, the device may include multiple signal emitters and a sensor to identify an orientation of the housing. The appropriate signal emitter may be selected based on the orientation of the housing as identified by the sensor. For another embodiment, the device may include a mechanism to redirect a source signal from a signal emitter in an appropriate direction based on the orientation of the housing.