发明授权
US08268844B2 Crystals of isopropyl ester of N-(2,6-dichlorobenzoyl)-4-[6-(methylamino)methyl-1-methyl-2,4-dioxo-1,4-dihydroquinazoline-3(2H)-yl]-l-phenylalanine hydrochloride, production method thereof and use thereof
有权
N-(2,6-二氯苯甲酰基)-4- [6-(甲基氨基)甲基-1-甲基-2,4-二氧代-1,4-二氢喹唑啉-3(2H) - 基] -1的异丙酯的晶体 苯丙氨酸盐酸盐,其制备方法和用途
- 专利标题: Crystals of isopropyl ester of N-(2,6-dichlorobenzoyl)-4-[6-(methylamino)methyl-1-methyl-2,4-dioxo-1,4-dihydroquinazoline-3(2H)-yl]-l-phenylalanine hydrochloride, production method thereof and use thereof
- 专利标题(中): N-(2,6-二氯苯甲酰基)-4- [6-(甲基氨基)甲基-1-甲基-2,4-二氧代-1,4-二氢喹唑啉-3(2H) - 基] -1的异丙酯的晶体 苯丙氨酸盐酸盐,其制备方法和用途
-
申请号: US12885936申请日: 2010-09-20
-
公开(公告)号: US08268844B2公开(公告)日: 2012-09-18
- 发明人: Koichi Fujita , Shinichiro Takahashi , Tatsuya Okuzumi , Tatsuhiro Yamada , Kotaro Okado , Noriyasu Kataoka , Haruko Hirashima , Hideyuki Yamaguchi
- 申请人: Koichi Fujita , Shinichiro Takahashi , Tatsuya Okuzumi , Tatsuhiro Yamada , Kotaro Okado , Noriyasu Kataoka , Haruko Hirashima , Hideyuki Yamaguchi
- 申请人地址: JP Tokyo
- 专利权人: Ajinomoto Co., Inc.
- 当前专利权人: Ajinomoto Co., Inc.
- 当前专利权人地址: JP Tokyo
- 代理机构: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权: JP2005-181219 20050621
- 主分类号: A61K31/517
- IPC分类号: A61K31/517
摘要:
Crystals of isopropyl ester of N-(2,6-dichlorobenzoyl)-4-[6-(methylamino)methyl-1-methyl-2,4-dioxo-1,4-dihydroquinazoline-3(2H)-yl]-L-phenylalanine hydrochloride: are useful as α4 integrin inhibitors.
公开/授权文献
信息查询
IPC分类: