发明授权
- 专利标题： Modified Vaccinia Ankara virus variant
- 专利标题（中）： 改良牛痘安卡拉病毒变体
-
申请号： US13053361申请日： 2011-03-22
-
公开(公告)号： US08268325B2公开(公告)日： 2012-09-18
- 发明人: Paul Chaplin , Paul Howley , Christine Meisinger-Henschel
- 申请人： Paul Chaplin , Paul Howley , Christine Meisinger-Henschel
- 申请人地址： DK Kvistgaard
- 专利权人： Bavarian Nordic A/S
- 当前专利权人： Bavarian Nordic A/S
- 当前专利权人地址： DK Kvistgaard
- 代理机构： Law Office of Salvatore Arrigo and Scott Lee, LLP
- 优先权： DK200001764 20001123
- 主分类号： A61K39/12
- IPC分类号： A61K39/12
摘要：
The present invention provides an attenuated virus, which is derived from Modified Vaccinia Ankara virus, wherein the MVA-BN virus, or a derivative thereof, induces at least substantially the same level of immunity in vaccinia virus prime/vaccina virus boost regimes when compared to DNA prime/vaccinia virus boost regimes. It further describes recombinant viruses derived from this virus and the use of the virus, or its recombinants, as a medicament or vaccine. A method is provided for inducing an immune response in individuals who may be immune-compromised, receiving antiviral therapy, or have a pre-existing immunity to the vaccine virus.
公开/授权文献
- US20110182932A1 MODIFIED VACCINIA ANKARA VIRUS VARIANT 公开/授权日：2011-07-28
信息查询
