发明授权
US08202688B2 Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
有权
使用含有未甲基化CpG二核苷酸的核酸作为佐剂
- 专利标题： Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
- 专利标题（中）： 使用含有未甲基化CpG二核苷酸的核酸作为佐剂
-
申请号： US10300247申请日： 2002-11-20
-
公开(公告)号： US08202688B2公开(公告)日： 2012-06-19
- 发明人: Heather L. Davis , Joachim Schorr , Arthur M. Krieg
- 申请人： Heather L. Davis , Joachim Schorr , Arthur M. Krieg
- 申请人地址： US IA Iowa City DE Dusseldorf CA Ottawa
- 专利权人： University of Iowa Research Foundation,Coley Pharmaceutical GmbH,Ottawa Health Research Institute
- 当前专利权人： University of Iowa Research Foundation,Coley Pharmaceutical GmbH,Ottawa Health Research Institute
- 当前专利权人地址： US IA Iowa City DE Dusseldorf CA Ottawa
- 代理机构： Wolf, Greenfield & Sacks, P.C.
- 代理商 Gregg C. Benson
- 主分类号： C12Q1/70
- IPC分类号： C12Q1/70 ; C12Q1/68 ; C12N15/11 ; A61K48/00
摘要：
The present invention relates generally to adjuvants, and in particular to methods and products utilizing a synergistic combination of immunostimulatory oligonucleotides having at least one unmethylated CpG dinucleotide (CpG ODN) and a non-nucleic acid adjuvant. Such combinations of adjuvants may be used with an antigen or alone. The present invention also relates to methods and products utilizing immunostimulatory oligonucleotides having at least one unmethylated CpG dinucleotide (CpG ODN) for induction of cellular immunity in infants.
公开/授权文献
信息查询
