发明授权
- 专利标题： Purification method of lactone compounds containing unsaturated alkyl group by extraction with silver ion solution
- 专利标题（中）： 用银离子溶液提取含有不饱和烷基的内酯化合物的纯化方法
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申请号： US13051948申请日： 2011-03-18
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公开(公告)号： US08193345B2公开(公告)日： 2012-06-05
- 发明人: Jae Jong Kim , Si Kyu Lim , Mi Ok Lee , Sang Myoun Lim , Bo-mi Lee , Dong Hwan Kim , Keum Soon Lee , Jeoung Hyun Ryu
- 申请人： Jae Jong Kim , Si Kyu Lim , Mi Ok Lee , Sang Myoun Lim , Bo-mi Lee , Dong Hwan Kim , Keum Soon Lee , Jeoung Hyun Ryu
- 申请人地址： KR Daejeon
- 专利权人： Genotech Corp.
- 当前专利权人： Genotech Corp.
- 当前专利权人地址： KR Daejeon
- 代理机构： Knobbe, Martens, Olson & Bear, LLP
- 优先权： KR10-2008-0091523 20080918
- 主分类号： C07D498/16
- IPC分类号： C07D498/16
摘要：
The present invention relates to a method for separating and purifying a lactone compound with an unsaturated alkyl group from a lactone compound with a saturated alkyl group which is an analog thereof. More specifically, the present invention relates to a method for effectively separating a lactone compound with an unsaturated alkyl group such as FK506 at high purity by extraction with a silver ion (Ag+) solution without use of column chromatography.
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