发明授权
US08183525B2 Method and system for analysing a dose formulation of a metered dose device
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用于分析计量剂量装置的剂量配方的方法和系统
- 专利标题: Method and system for analysing a dose formulation of a metered dose device
- 专利标题(中): 用于分析计量剂量装置的剂量配方的方法和系统
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申请号: US12523293申请日: 2008-01-15
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公开(公告)号: US08183525B2公开(公告)日: 2012-05-22
- 发明人: Frank Chambers , Andrew Feilden
- 申请人: Frank Chambers , Andrew Feilden
- 申请人地址: SE Sodertalje
- 专利权人: Astrazeneca AB
- 当前专利权人: Astrazeneca AB
- 当前专利权人地址: SE Sodertalje
- 代理机构: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- 国际申请: PCT/SE2008/000027 WO 20080115
- 国际公布: WO2008/088270 WO 20080724
- 主分类号: H01J49/00
- IPC分类号: H01J49/00
摘要:
One aspect of the invention features a method of analyzing dose metered devices by: spraying an aerosol from a metered dose device directly into a spray chamber of a mass spectrometer detector by firing a dose from a metered dose device, for example a pMDI, by depressing the pMDI in its actuator, which spraying step is optionally preceded by a step of priming the drug container of the metered dose device; ionizing the aerosol; and identifying and quantifying the content of the dose using the detector.
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