Invention Grant
US08173614B2 Therapeuting compositions comprising an RNAi agent and a neurotrophic factor and methods of use thereof
有权
包含RNAi剂和神经营养因子的治疗组合物及其使用方法
- Patent Title: Therapeuting compositions comprising an RNAi agent and a neurotrophic factor and methods of use thereof
- Patent Title (中): 包含RNAi剂和神经营养因子的治疗组合物及其使用方法
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Application No.: US12580973Application Date: 2009-10-16
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Publication No.: US08173614B2Publication Date: 2012-05-08
- Inventor: Eric Neal Burright , William F. Kaemmerer , Deepak Ramesh Thakker , Jennifer Heisel
- Applicant: Eric Neal Burright , William F. Kaemmerer , Deepak Ramesh Thakker , Jennifer Heisel
- Applicant Address: US MN Minneapolis
- Assignee: Medtronic, Inc.
- Current Assignee: Medtronic, Inc.
- Current Assignee Address: US MN Minneapolis
- Agency: Fox Rothschild LLP
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K31/70 ; A61K48/00 ; C07H21/02 ; C07H21/04
Abstract:
The invention provides novel combination therapies for treating Huntington's disease which comprise a) BDNF or suitable fragments thereof and b) agents capable of causing inhibition of a gene responsible for the neurodegenerative disease. The invention provides nucleic acid sequences, methods, and systems suitable for applications of these combination therapies.
Public/Granted literature
- US20100113351A1 Therapeuting Compositions Comprising an RNAi Agent and a Neurotrophic Factor and Methods of Use Thereof Public/Granted day:2010-05-06
Information query
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