Invention Grant
- Patent Title: Aminodiazepines as toll-like receptor modulators
- Patent Title (中): 氨基二氮卓类作为长期受体调节剂
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Application No.: US12064196Application Date: 2006-08-17
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Publication No.: US08163738B2Publication Date: 2012-04-24
- Inventor: George A. Doherty , Zachary Jones
- Applicant: George A. Doherty , Zachary Jones
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- Agency: Viksnins Harris & Padys
- Agent John R. Moore; Corey M. Williams
- International Application: PCT/US2006/032099 WO 20060817
- International Announcement: WO2007/040840 WO 20070412
- Main IPC: A61P37/02
- IPC: A61P37/02 ; A61K31/5513 ; C07D243/20
Abstract:
Provided are compositions and methods useful for modulation signaling through the Toll-like receptor TLR8. The compositions and methods have use in the treatment of autoimmunity, inflammation allergy, asthma, graft rejection, graft versus host disease, infection, sepsis, cancer and immunodeficiency.
Public/Granted literature
- US20080306050A1 Aminodiazepines as Toll-Like Receptor Modulators Public/Granted day:2008-12-11
Information query
