Invention Grant
US08158590B2 Triazole-containing releasable linkers, conjugates thereof, and methods of preparation
有权
含有三唑的可释放接头，其缀合物及其制备方法
- Patent Title: Triazole-containing releasable linkers, conjugates thereof, and methods of preparation
- Patent Title (中): 含有三唑的可释放接头，其缀合物及其制备方法
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Application No.: US11997981Application Date: 2006-08-03
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Publication No.: US08158590B2Publication Date: 2012-04-17
- Inventor: Patrick Henry Beusker , Franciscus Marinus Hendrikus De Groot
- Applicant: Patrick Henry Beusker , Franciscus Marinus Hendrikus De Groot
- Applicant Address: NL Nijmegen
- Assignee: Syntarga B.V.
- Current Assignee: Syntarga B.V.
- Current Assignee Address: NL Nijmegen
- Agency: K&L Gates LLP
- Priority: WOPCT/NL2005/000576 20050805
- International Application: PCT/NL2006/050192 WO 20060803
- International Announcement: WO2007/018431 WO 20070215
- Main IPC: A61K38/07
- IPC: A61K38/07 ; A61P31/00
Abstract:
This invention relates to compounds comprising one or more therapeutic and/or diagnostic moieties and one or more functional moieties linked together via one or more triazole-containing linkers and to their intermediates and methods of their preparation. The triazole-containing linker may optionally contain one or more conditionally-cleavable or conditionally-transformable moieties and one or more spacer systems in between said moiety/moieties and the one or more therapeutic and/or diagnostic moieties.
Public/Granted literature
- US20080311136A1 Triazole-Containing Releasable Linkers, Conjugates Thereof, and Methods of Preparation Public/Granted day:2008-12-18
Information query
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