- 专利标题： Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases
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申请号： US12151585申请日： 2008-05-07
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公开(公告)号： US08148369B2公开(公告)日： 2012-04-03
- 发明人: Martin James Inglis Andrews , Mark Stuart Chambers , Wolfgang Schmidt , Giovanni Alessandro Tricarico , Grégory Louis Joseph Bar , Kim Louise Hirst , Olga Raquel Pinto Santos Oliveira Roussel , Juha Andrew Clase
- 申请人： Martin James Inglis Andrews , Mark Stuart Chambers , Wolfgang Schmidt , Giovanni Alessandro Tricarico , Grégory Louis Joseph Bar , Kim Louise Hirst , Olga Raquel Pinto Santos Oliveira Roussel , Juha Andrew Clase
- 申请人地址： BE Beerse
- 专利权人： Janssen Pharmaceutica NV
- 当前专利权人： Janssen Pharmaceutica NV
- 当前专利权人地址： BE Beerse
- 主分类号： A61K31/50
- IPC分类号： A61K31/50 ; A61K31/535 ; C07D413/14 ; C07D471/04
摘要：
Novel fused pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammation, rheumatoid arthritis and others.
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