Invention Grant
US08138155B2 Compounds for intracellular delivery of therapeutic moieties to nerve cells
有权
将治疗性部分细胞内递送给神经细胞的化合物
- Patent Title: Compounds for intracellular delivery of therapeutic moieties to nerve cells
- Patent Title (中): 将治疗性部分细胞内递送给神经细胞的化合物
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Application No.: US12749339Application Date: 2010-03-29
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Publication No.: US08138155B2Publication Date: 2012-03-20
- Inventor: Robert R. Webb , Constance A. McKee
- Applicant: Robert R. Webb , Constance A. McKee
- Applicant Address: US CA Woodside
- Assignee: Manzanita Pharmaceuticals, Inc.
- Current Assignee: Manzanita Pharmaceuticals, Inc.
- Current Assignee Address: US CA Woodside
- Agency: Bozicevic, Field & Francis LLP
- Agent Carol L. Francis
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61K47/28 ; A61K47/42 ; C07K14/48
Abstract:
A compound for delivering a non-cytotoxic therapeutic moiety into nerve cells, the compound having the general formula: B-L-TM where: B is a binding agent capable of selectively binding to a nerve cell surface receptor and mediating absorption of the compound by the nerve cell; TM is a therapeutic moiety which has a non-cytotoxic therapeutic effect when absorbed by a nerve cell; and L is a linker coupling B to TM.
Public/Granted literature
- US20100266492A1 COMPOUNDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOIETIES TO NERVE CELLS Public/Granted day:2010-10-21
Information query
IPC分类:
