Techniques are disclosed for eliminating or otherwise sufficiently suppressing spurious signals. The techniques are particularly useful in applications such as those that employ aggressor frequency sources along with a frequency conversion or mixing function, and especially applications implemented as a system-on-chip. In the spur-training mode, a spur-canceller circuit identifies spurious tones associated with the host system to neutralize those tones when running in a normal mode. The tones are neutralized using a comb generator with variable phase and gain by way of cancellation with comb output signals having substantially the same amplitude and a phase that is 180° out of phase with the aggressor tone to be cancelled.