发明授权
- 专利标题： Methods of use of the TACI/TACI-L interaction
- 专利标题（中）： TACI / TACI-L相互作用的使用方法
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申请号： US12614109申请日： 2009-11-06
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公开(公告)号： US08133976B2公开(公告)日： 2012-03-13
- 发明人: Raymond G. Goodwin , Wanwan S. Din
- 申请人： Raymond G. Goodwin , Wanwan S. Din
- 申请人地址： US CA Thousand Oaks
- 专利权人： Immunex Corporation
- 当前专利权人： Immunex Corporation
- 当前专利权人地址： US CA Thousand Oaks
- 代理商 James E. Klaniecki
- 主分类号： C07K14/525
- IPC分类号： C07K14/525 ; C07K14/475 ; C07K14/715
摘要：
The invention discloses a novel interaction between a TNF receptor (TACI) and its interacting ligand (TACI-L). Also disclosed are methods of screening candidate molecules to determine potential antagonists and agonists of the TACI/TACI-L interaction. The use of the antagonists and agonists as therapeutics to treat autoimmune diseases, inflammation, and to inhibit graft vs. host rejections is further disclosed.
公开/授权文献
- US20100196404A1 METHODS OF USE OF THE TACI/TACI-L INTERACTION 公开/授权日：2010-08-05
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