- 专利标题: Immunostimulatory nucleic acid molecules
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申请号: US11067587申请日: 2005-02-25
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公开(公告)号: US08129351B2公开(公告)日: 2012-03-06
- 发明人: Arthur M. Krieg , Dennis Klinman , Alfred D. Steinberg
- 申请人: Arthur M. Krieg , Dennis Klinman , Alfred D. Steinberg
- 申请人地址: US IA Iowa City US NY New York US DC Washington
- 专利权人: The University of Iowa Research Foundation,Coley Pharmaceutical Group, Inc.,The United States of America as represented by the Secretary of the Department of Health and Human Services
- 当前专利权人: The University of Iowa Research Foundation,Coley Pharmaceutical Group, Inc.,The United States of America as represented by the Secretary of the Department of Health and Human Services
- 当前专利权人地址: US IA Iowa City US NY New York US DC Washington
- 代理机构: Wolf, Greenfield & Sacks, P.C.
- 代理商 Gregg C. Benson
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61K39/38 ; A61K39/145 ; A61K38/00 ; A61K31/70 ; A01N37/18 ; A01N43/04
摘要:
Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
公开/授权文献
- US20060003955A1 Immunostimulatory nucleic acid molecules 公开/授权日:2006-01-05
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