发明授权
US08124621B2 Substituted 1-amino-4-phenyl-dihydroisoquinolines, methods for the production thereof, use thereof as a medicament, and medicaments containing them
有权
取代的1-氨基-4-苯基 - 二氢异喹啉，其制备方法，作为药物的用途，以及含有它们的药物
- 专利标题： Substituted 1-amino-4-phenyl-dihydroisoquinolines, methods for the production thereof, use thereof as a medicament, and medicaments containing them
- 专利标题（中）： 取代的1-氨基-4-苯基 - 二氢异喹啉，其制备方法，作为药物的用途，以及含有它们的药物
-
申请号： US12212301申请日： 2008-09-17
-
公开(公告)号： US08124621B2公开(公告)日： 2012-02-28
- 发明人: Hans-Jochen Lang , John Weston , Uwe Heinelt
- 申请人： Hans-Jochen Lang , John Weston , Uwe Heinelt
- 申请人地址： FR Paris
- 专利权人： Sanofi-Aventis
- 当前专利权人： Sanofi-Aventis
- 当前专利权人地址： FR Paris
- 代理机构： Scully, Scott, Murphy & Presser, P.C.
- 优先权： DE102006012544 20060318
- 主分类号： C07D217/22
- IPC分类号： C07D217/22 ; A61K31/47
摘要：
The present invention relates to compounds useful in the prevention or treatment of various disorders such as acute or chronic renal failure, for impairments of biliary function, for respiratory impairments such as snoring or sleep apneas or for stroke, and pharmaceutical compositions comprising them. More specifically, the compounds of the present invention comprises substituted 1-amino-4-phenyl-dihydroisoquinolines and their derivatives of formula I: Wherein the substituents R1-R11 are more specifically defined hereinbelow. The claimed compounds of the present invention also include their pharmaceutically acceptable salts and trifluoroacetates thereof as well as methods for their preparation and pharmaceutical delivery systems thereof.
公开/授权文献
信息查询
