发明授权
- 专利标题： Viruses for the treatment of cellular proliferative disorders
- 专利标题（中）： 用于治疗细胞增殖性疾病的病毒
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申请号： US12761534申请日： 2010-04-16
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公开(公告)号： US08080241B2公开(公告)日： 2011-12-20
- 发明人: Matthew C. Coffey , Bradley G. Thompson
- 申请人： Matthew C. Coffey , Bradley G. Thompson
- 申请人地址： CA Calgary, Alberta
- 专利权人： Oncolytics Biotech Inc.
- 当前专利权人： Oncolytics Biotech Inc.
- 当前专利权人地址： CA Calgary, Alberta
- 代理机构： McKeon Meunier Carlin & Curfman, LLC
- 主分类号： A61K39/285
- IPC分类号： A61K39/285 ; A61K39/395 ; C12N15/00
摘要：
Methods for treating cell proliferative disorders by administering virus to proliferating cells having an activated Ras-pathway are disclosed. The virus is administered so that it ultimately directly contacts proliferating cells having an activated Ras-pathway. Proliferative disorders include but are not limited to neoplasms. The virus is selected from modified adenovirus, modified HSV, modified vaccinia virus and modified parapoxvirus orf virus. Also disclosed are methods for treating cell proliferative disorders by further administering an immunosuppressive agent.
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