发明授权
US08062844B2 Use of acid scavengers for the synthesis of standard length and long-mer nucleic acid arrays 有权
使用酸清除剂合成标准长度和长链核酸阵列

Use of acid scavengers for the synthesis of standard length and long-mer nucleic acid arrays
摘要:
Protective groups which may be cleaved with an activatable deprotecting reagents are employed to achieve a highly sensitive, high resolution, combinatorial synthesis of pattern arrays of diverse polymers. In preferred embodiments of the instant invention, the activatable deprotecting reagent is a photoacid generator and the protective groups are DMT for nucleic acids and tBOC for amino acids. This invention has a wide variety of applications and is particularly useful for the solid phase combinatorial synthesis of polymers.
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