Invention Grant
US08017736B2 Alpha-fetoprotein Immu31 antibodies and fusion proteins and methods of use thereof
有权
甲胎蛋白Immu31抗体和融合蛋白及其使用方法
- Patent Title: Alpha-fetoprotein Immu31 antibodies and fusion proteins and methods of use thereof
- Patent Title (中): 甲胎蛋白Immu31抗体和融合蛋白及其使用方法
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Application No.: US12359745Application Date: 2009-01-26
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Publication No.: US08017736B2Publication Date: 2011-09-13
- Inventor: Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- Applicant: Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- Applicant Address: US NJ Morris Plains
- Assignee: Immunomedics, Inc.
- Current Assignee: Immunomedics, Inc.
- Current Assignee Address: US NJ Morris Plains
- Agent Richard A. Nakashima
- Main IPC: C12P21/08
- IPC: C12P21/08
Abstract:
The present invention provides humanized, chimeric and human anti-alpha-fetoprotein antibodies, fusion proteins, and fragments thereof. The antibodies, fusion proteins, and fragments thereof, as well as combinations with other suitable antibodies, are useful for the treatment and diagnosis of hepatocellular carcinoma, hepatoblastoma, germ cell tumors carcinoma and other AFP-producing tumors.
Public/Granted literature
- US20100196989A1 Alpha-Fetoprotein Immu31 Antibodies and Fusion Proteins and Methods of Use Thereof Public/Granted day:2010-08-05
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