发明授权
US08012486B2 Composition for treating atopic dermatitis comprising hirsutenone as an active ingredient
有权
用于治疗特应性皮炎的组合物，其包含以高分子量酮为活性成分
- 专利标题： Composition for treating atopic dermatitis comprising hirsutenone as an active ingredient
- 专利标题（中）： 用于治疗特应性皮炎的组合物，其包含以高分子量酮为活性成分
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申请号： US12454520申请日： 2009-05-19
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公开(公告)号： US08012486B2公开(公告)日： 2011-09-06
- 发明人: Min Won Lee , Young Wook Choi , Seong Jun Seo , Do Ik Lee , Hyoweon Bang , Chung Soo Lee , Jong Chan Lee , Soon-Chul Myung , Mi-Kyung Lee , Seong Soo Joo , Sun Eun Choi
- 申请人： Min Won Lee , Young Wook Choi , Seong Jun Seo , Do Ik Lee , Hyoweon Bang , Chung Soo Lee , Jong Chan Lee , Soon-Chul Myung , Mi-Kyung Lee , Seong Soo Joo , Sun Eun Choi
- 申请人地址： KR Seoul
- 专利权人： Chung-Ang University Industry Academic Cooperation Foundation
- 当前专利权人： Chung-Ang University Industry Academic Cooperation Foundation
- 当前专利权人地址： KR Seoul
- 代理机构： Clark & Elbing LLP
- 优先权： KR10-2009-0006646 20090128
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K8/02 ; A61K47/00 ; A61K31/12
摘要：
The present invention relates to a composition for treating atopic dermatitis comprising hirsutenone as an active ingredient. Hirsutenone as the active ingredient of the present composition decreases the number of eosinophil and the level of IgE increased in atopic dermatitis and remarkably reduces expression amounts of immune regulatory cytokine (e.g., IL-4, IL-5 and IL-13) associated with atopic dermatitis. In addition, hirsutenone decreases COX-2 and iNOS expression. Hirsutenone as the active ingredient of the present composition could be effectively used in drugs, cosmetics and foods for treating atopic dermatitis or relieving a symptom of atopic dermatitis.
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