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发明授权
US07977427B2 Method involving 1-benzotriazolyl carbonate esters of polymers 有权
涉及聚合物的1-苯并三唑基碳酸酯的方法

Method involving 1-benzotriazolyl carbonate esters of polymers
摘要：
The invention provides a method comprising the steps of (i) reacting a water-soluble and non-peptidic polymer having two or more terminal hydroxyl groups with di(1-benzotriazolyl)carbonate to form a water-soluble and non-peptidic polymer having two or more 1-benzotriazolylcarbonate ester groups; and (ii) reacting the water-soluble and non-peptidic polymer having two or more 1-benzotriazolylcarbonate ester groups with a water-soluble and non-peptidic polymer having three or more primary amino groups under conditions effective to form a cross-linked polymer composition.
摘要（中）：

本发明提供了一种方法，其包括以下步骤：（i）使具有两个或多个末端羟基的水溶性和非肽类聚合物与二（1-苯并三唑基）碳酸酯反应，形成具有两个 或更多的1-苯并三唑基碳酸酯基团; 和（ii）在有效形成交联聚合物的条件下使具有两个或多个1-苯并三唑基碳酸酯基团的水溶性和非肽类聚合物与具有三个或更多个伯氨基的水溶性和非肽性聚合物反应 组成。

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