发明授权
US07977328B2 Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes
失效
用作治疗糖尿病的GLK激活剂的杂芳基苯甲酰胺衍生物
- 专利标题： Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes
- 专利标题（中）： 用作治疗糖尿病的GLK激活剂的杂芳基苯甲酰胺衍生物
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申请号： US12256254申请日： 2008-10-22
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公开(公告)号： US07977328B2公开(公告)日： 2011-07-12
- 发明人: Darren McKerrecher , Kurt Gordon Pike , Michael James Waring
- 申请人： Darren McKerrecher , Kurt Gordon Pike , Michael James Waring
- 申请人地址： SE Sodertalje
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 当前专利权人地址： SE Sodertalje
- 代理机构： Morgan Lewis & Bockius LLP
- 优先权： GB0514173.4 20050709; GB0516297.9 20050809; GB0523862.1 20051124; GB0524589.9 20051202; GB0607977.6 20060422
- 主分类号： A61K31/397
- IPC分类号： A61K31/397 ; A61P3/10 ; A61P3/04 ; C07D417/12 ; C07D401/12 ; C07D413/12
摘要：
Compounds of formula (I) wherein R1, HET-1 and HET-2 are as described in the specification, and their salts and pro-drugs, are activators of glucokinase (GLK) and are thereby useful in the treatment of, for example, type 2 diabetes. Processes for preparing compounds of formula (I) are also described.
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