A cavitation system in which a source gas, e.g., a reactant, is loaded into the cavitation medium prior to cavitation is provided. The cavitation system includes a cavitation chamber with suitable cavitation drivers and a cavitation medium reservoir, the chamber and reservoir being flexibly coupled together via a pair of conduits. The conduits can be fabricated from a plastic or, as is preferred for higher temperature liquids, a metal. Typically metal conduits are formed into a coil, thus providing the desired flexibility. Flexibility is required in order to allow the relative positions of the cavitation chamber and the cavitation medium reservoir to be varied. The system is configured such that the cavitation fluid will flow out of the cavitation chamber, through the lower coupling conduit and into the cavitation medium reservoir when the chamber is positioned higher than the reservoir, and flow out of the cavitation medium reservoir, through the lower coupling conduit and into the cavitation chamber when the reservoir is positioned higher than the chamber. As a consequence of this configuration, cavitation fluid can be readily exchanged between the cavitation chamber and the cavitation medium reservoir, thereby aiding the degassing process as well as providing a means of replenishing reactant-depleted cavitation medium.