发明授权
US07928105B2 Substituted 6a,7,8,9-tetrahydropyrido[3,2-e]pyrrolo[1,2-a]pyrazin-6(5H)-ones
有权
取代的6a，7,8,9-四氢吡啶并[3,2-e]吡咯并[1,2-a]吡嗪-6（5H） - 酮
![Substituted 6a,7,8,9-tetrahydropyrido[3,2-e]pyrrolo[1,2-a]pyrazin-6(5H)-ones](/docs/US/2011-04-19/US07928105B2/abs.jpg.600x600.jpg)
- 专利标题： Substituted 6a,7,8,9-tetrahydropyrido[3,2-e]pyrrolo[1,2-a]pyrazin-6(5H)-ones
- 专利标题（中）： 取代的6a，7,8,9-四氢吡啶并[3,2-e]吡咯并[1,2-a]吡嗪-6（5H） - 酮
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申请号： US12691668申请日： 2010-01-21
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公开(公告)号： US07928105B2公开(公告)日： 2011-04-19
- 发明人: Anthony R. Gangloff , Andrew John Jennings , Benjamin Jones , Andre A. Kiryanov
- 申请人： Anthony R. Gangloff , Andrew John Jennings , Benjamin Jones , Andre A. Kiryanov
- 申请人地址： JP Osaka
- 专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人地址： JP Osaka
- 代理商 Matthew J. Russo; Mitchell R. Brustein
- 主分类号： A61K31/495
- IPC分类号： A61K31/495
![Substituted 6a,7,8,9-tetrahydropyrido[3,2-e]pyrrolo[1,2-a]pyrazin-6(5H)-ones](/abs-image/US/2011/04/19/US07928105B2/abs.jpg.150x150.jpg)
摘要：
Disclosed are compounds of the following formula: in which R1, R2, R5, R6, R7, R31, u, and X are defined in the specification. Also disclosed are pharmaceutical compositions, kits, and articles of manufacture, which contain the compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions related to PARP activity.
公开/授权文献
- US20100190763A1 Poly (ADP-Ribose) Polymerase (PARP) Inhibitors 公开/授权日：2010-07-29
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