Performance problems or other conditions are analyzed in a system comprising a plurality of endpoint devices and an associated centralized or distributed controller. End-to-end measurements are obtained for respective paths through the network, for example, using communications between the endpoint devices. For a given end-to-end measurement obtained for a particular one of the paths, a value of a performance indicator for the path is determined and the performance indicator value is assigned to each of a plurality of links of the path. The determining and assigning operations are repeated for additional ones of the end-to-end measurements, the links are grouped into one or more exculpation or inculpation sets based on how many times a particular performance indicator value has been assigned to each of the links, and the one or more sets are utilized to determine, for example, the location of a performance problem in the network.