发明授权
US07923571B2 Process for preparing substituted 2-alkoxycarbonyl-3-aminothiophenes 有权
取代的2-烷氧基羰基-3-氨基噻吩的制备方法

  • 专利标题: Process for preparing substituted 2-alkoxycarbonyl-3-aminothiophenes
  • 专利标题(中): 取代的2-烷氧基羰基-3-氨基噻吩的制备方法
  • 申请号: US11722506
    申请日: 2005-12-14
  • 公开(公告)号: US07923571B2
    公开(公告)日: 2011-04-12
  • 发明人: Thomas Geller
  • 申请人: Thomas Geller
  • 申请人地址: DE Monheim
  • 专利权人: Bayer Cropscience AG
  • 当前专利权人: Bayer Cropscience AG
  • 当前专利权人地址: DE Monheim
  • 代理机构: Baker Donelson Bearman, Caldwell & Berkowitz, PC
  • 优先权: DE102004063191 20041229
  • 国际申请: PCT/EP2005/013406 WO 20051214
  • 国际公布: WO2006/072375 WO 20060713
  • 主分类号: C07D333/36
  • IPC分类号: C07D333/36
Process for preparing substituted 2-alkoxycarbonyl-3-aminothiophenes
摘要:
The present invention relates to a process for preparing 4-alkoxycarbonyl-3-aminothiophenes of the general formula (I) and/or their hydrochlorides of the formula (I)′ in which R1 and R2 are each as defined in the description, and/or their mono- or bisacetylated or mono- or bisformylated form, by reacting enamines of the formula (II) in which R1 and R2 are each as defined in the description, and/or their mono- or bisacetylated or mono- or bisformylated form, with a chlorinating agent in the presence of one or more diluents, and also to a process for preparing the compounds of the formula (II).
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