Invention Grant
![5-anilinoimidazo[1,5-a]-pyridines inhibitors of MEK kinase](/docs/US/2011-04-12/US07923456B2/abs.jpg.600x600.jpg)
- Patent Title: 5-anilinoimidazo[1,5-a]-pyridines inhibitors of MEK kinase
- Patent Title (中): 5-苯胺基咪唑并[1,5-a] - 吡啶抑制剂
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Application No.: US12432529Application Date: 2009-04-29
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Publication No.: US07923456B2Publication Date: 2011-04-12
- Inventor: Stephen Price , Robert Heald , Wendy Lee , Mark E. Zak , Joanne Frances Mary Hewitt
- Applicant: Stephen Price , Robert Heald , Wendy Lee , Mark E. Zak , Joanne Frances Mary Hewitt
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Brian L. Buckwalter
- Main IPC: A61K31/44
- IPC: A61K31/44
![5-anilinoimidazo[1,5-a]-pyridines inhibitors of MEK kinase](/abs-image/US/2011/04/12/US07923456B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to imidazopyridines of formula I with anti-cancer and/or anti-inflammatory activity and more specifically to imidazopyridines which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.
Public/Granted literature
- US20100004269A1 5-ANILINOIMIDAZOPYRIDINES AND METHODS OF USE Public/Granted day:2010-01-07
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