发明授权
US07923254B2 Method for studying, determining or evaluating pharmacological actions of a test substance on an sart stressed animal
失效
用于研究,确定或评估测试物质对萨特强调动物的药理作用的方法
- 专利标题: Method for studying, determining or evaluating pharmacological actions of a test substance on an sart stressed animal
- 专利标题(中): 用于研究,确定或评估测试物质对萨特强调动物的药理作用的方法
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申请号: US12310746申请日: 2007-09-05
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公开(公告)号: US07923254B2公开(公告)日: 2011-04-12
- 发明人: Kusuki Nishioka , Tomohiro Kato , Hiroki Fujisawa
- 申请人: Kusuki Nishioka , Tomohiro Kato , Hiroki Fujisawa
- 申请人地址: JP Osaka
- 专利权人: Nippon Zoki Pharmaceutical Co., Ltd.
- 当前专利权人: Nippon Zoki Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Osaka
- 代理机构: Oliff & Berridge, PLC
- 优先权: JP2006-240924 20060906
- 国际申请: PCT/JP2007/067291 WO 20070905
- 国际公布: WO2008/029836 WO 20080313
- 主分类号: G01N33/48
- IPC分类号: G01N33/48
摘要:
A method for studying, determining or evaluating a pharmacological action of a test substance, the method including subjecting the brain tissue of an SART stressed animal administered with the test substance to an expression proteome analysis, where expression changes of NSF (N-ethylmaleimide sensitive fusion protein), which is or is not modified after translation, in the SART stressed animal administered with the test substance as compared with an SART stressed animal to which a test substance is not administered is used as an index.
公开/授权文献
- US20090272649A1 Method for study, determination or evaluation 公开/授权日:2009-11-05
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