- 专利标题: Fungal cell wall synthesis gene
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申请号: US12103600申请日: 2008-04-15
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公开(公告)号: US07910712B2公开(公告)日: 2011-03-22
- 发明人: Kappei Tsukahara , Katsura Hata , Koji Sagane , Kazutaka Nakamoto , Mamiko Tsuchiya , Naoaki Watanabe , Fuminori Ohba , Itaru Tsukada , Norihiro Ueda , Keigo Tanaka , Junko Kai
- 申请人: Kappei Tsukahara , Katsura Hata , Koji Sagane , Kazutaka Nakamoto , Mamiko Tsuchiya , Naoaki Watanabe , Fuminori Ohba , Itaru Tsukada , Norihiro Ueda , Keigo Tanaka , Junko Kai
- 申请人地址: JP Tokyo
- 专利权人: Eisai R&D Management Co., Ltd
- 当前专利权人: Eisai R&D Management Co., Ltd
- 当前专利权人地址: JP Tokyo
- 代理机构: Kilpatrick Townsend and Stockton LLP.
- 代理商 M. Henry Heines
- 优先权: JP2000-206968 20000707; JP2000-316027 20001017
- 主分类号: C12N15/80
- IPC分类号: C12N15/80 ; A61K36/06 ; A61K38/00
摘要:
The present invention provides isolated DNA encoding a GWT1 protein having activity to confer resistance of a fungus against a compound of formula Ia, and wherein a defect of a function of the GWT1 protein leads to a decrease in the amount of a glycosylphosphatidylinositol (GPI)-anchored protein in the cell wall of a fungus.
公开/授权文献
- US20090325228A1 FUNGAL CELL WALL SYNTHESIS GENE 公开/授权日:2009-12-31
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