发明授权
- 专利标题： Small molecule antagonists of XIAP family proteins
- 专利标题（中）： XIAP家族蛋白的小分子拮抗剂
-
申请号： US10594200申请日： 2005-03-22
-
公开(公告)号： US07910621B2公开(公告)日： 2011-03-22
- 发明人: Jianyong Chen , Zaneta Nikolovska-Coleska , Dajun Yang , Shaomeng Wang , Haiying Sun , Liang Xu , Zengjian Hu
- 申请人： Jianyong Chen , Zaneta Nikolovska-Coleska , Dajun Yang , Shaomeng Wang , Haiying Sun , Liang Xu , Zengjian Hu
- 申请人地址： US MI Ann Arbor
- 专利权人： The Regents of the University of Michigan
- 当前专利权人： The Regents of the University of Michigan
- 当前专利权人地址： US MI Ann Arbor
- 代理机构： Casimir Jones SC
- 国际申请： PCT/US2005/009378 WO 20050322
- 国际公布： WO2005/092326 WO 20051006
- 主分类号： A61K31/352
- IPC分类号： A61K31/352 ; C07D311/30
摘要：
The present invention relates to naturally occurring and chemically synthesized small molecule antagonists of XIAP family proteins. In particular, the present invention provides embelin and other XIAP inhibitors and methods of using these compounds as antagonists of the anti-apoptotic effects of XIAP family member proteins. The present invention also provides methods for treating diseases and pathologies (e.g., neoplastic diseases).
公开/授权文献
- US20080021095A1 Small Molecule Antagonists of Xiap Family Proteins 公开/授权日：2008-01-24
信息查询
