发明授权
US07910128B2 Use of a mixture of two or more enteric materials to regulate drug release via membrane or matrix for systemic therapeutics
有权
使用两种或多种肠溶性物质的混合物来调节药物释放通过膜或基质进行全身治疗
- 专利标题: Use of a mixture of two or more enteric materials to regulate drug release via membrane or matrix for systemic therapeutics
- 专利标题(中): 使用两种或多种肠溶性物质的混合物来调节药物释放通过膜或基质进行全身治疗
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申请号: US10751766申请日: 2004-01-05
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公开(公告)号: US07910128B2公开(公告)日: 2011-03-22
- 发明人: Rong-Kun Chang , Niraj Shah
- 申请人: Rong-Kun Chang , Niraj Shah
- 申请人地址: US MD Rockville
- 专利权人: Supernus Pharmaceuticals, Inc.
- 当前专利权人: Supernus Pharmaceuticals, Inc.
- 当前专利权人地址: US MD Rockville
- 代理机构: Foley & Lardner LLP
- 代理商 Stephen B. Maebius; Sunit Talapatra
- 主分类号: A61F13/00
- IPC分类号: A61F13/00 ; A61K9/24
摘要:
Disclosed are pharmaceutical compositions, particularly oral dosage forms, which comprise two or more enteric coating materials, either as a coating or as part of a matrix dosage form, and methods of making and using the same. The compositions are characterized by having a sustained release profile at lower pH and an accelerated dissolution profile at higher pH.
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