Invention Grant
- Patent Title: 1,5-diphenylpyrazoles II as HSP90 inhibitors
- Patent Title (中): 1,5-二苯基吡唑II作为HSP90抑制剂
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Application No.: US12301067Application Date: 2007-04-20
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Publication No.: US07906657B2Publication Date: 2011-03-15
- Inventor: Hans-Michael Eggenweiler , Michael Wolf , Hans-Peter Buchstaller , Christian Sirrenberg
- Applicant: Hans-Michael Eggenweiler , Michael Wolf , Hans-Peter Buchstaller , Christian Sirrenberg
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
- Current Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: DE102006023336 20060518
- International Application: PCT/EP2007/003469 WO 20070420
- International Announcement: WO2007/134677 WO 20071129
- Main IPC: C07D261/06
- IPC: C07D261/06 ; C07D231/12 ; C07D401/10 ; C07D403/10 ; A61K31/501 ; A61K31/497 ; A61K31/454 ; A61K31/4427 ; A61K31/415
Abstract:
Novel 1,5-diphenylpyrazole derivatives of the formula (I) in which R1-R6 have the meanings indicated in claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.
Public/Granted literature
- US20090325974A1 1,5-DIPHENYLPYRAZOLES II AS HSP90 INHIBITORS Public/Granted day:2009-12-31
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