发明授权
US07875621B2 Substituted 2-alkyl quinazolinone derivatives as PARP inhibitors
有权
取代的2-烷基喹唑啉酮衍生物作为PARP抑制剂
- 专利标题： Substituted 2-alkyl quinazolinone derivatives as PARP inhibitors
- 专利标题（中）： 取代的2-烷基喹唑啉酮衍生物作为PARP抑制剂
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申请号： US11570023申请日： 2005-06-28
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公开(公告)号： US07875621B2公开(公告)日： 2011-01-25
- 发明人: Marcel Jozef Maria Van Der Aa , Albertus Henricus Maria Theresia Van Heertum , Jacobus Alphonsus Josephus Van Dun , Maria Victorina Francisca Somers , Walter Boudewijin Leopold Wouters
- 申请人： Marcel Jozef Maria Van Der Aa , Albertus Henricus Maria Theresia Van Heertum , Jacobus Alphonsus Josephus Van Dun , Maria Victorina Francisca Somers , Walter Boudewijin Leopold Wouters
- 申请人地址： BE
- 专利权人： Janssen Pharmaceutica NV
- 当前专利权人： Janssen Pharmaceutica NV
- 当前专利权人地址： BE
- 优先权： EP04076887 20040630
- 国际申请： PCT/EP2005/053034 WO 20050628
- 国际公布： WO2006/003150 WO 20060112
- 主分类号： A61K31/517
- IPC分类号： A61K31/517
摘要：
The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions containing compounds of formula (I) wherein R1, R3, L, X, Y and Z have defined meanings.
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