The present invention provides a humidification system with membranes of different species, in which a material having a high humidification performance and capable of being swollen with water is arranged in the center of a hollow fiber membrane bundle disposed in a hollow fiber membrane module and a material that is not swollen with water is disposed on the outside thereof. Accordingly, using the humidification system of the invention, it is possible to provide the same level of humidification performance as the existing humidification system, manufacture the humidification system at low cost, and solve various problems such as a flooding phenomenon of a fuel cell stack and an increase in load on an air blower.