发明授权
US07854918B2 Composition for medical use having improved water-solubility of peptide and metal-labeling efficiency and preparation for medical use comprising metal-labeled peptide
有权
具有改进的肽的水溶性和金属标记效率的用于医疗用途的组合物和包含金属标记的肽的用于医疗用途的制剂
- 专利标题： Composition for medical use having improved water-solubility of peptide and metal-labeling efficiency and preparation for medical use comprising metal-labeled peptide
- 专利标题（中）： 具有改进的肽的水溶性和金属标记效率的用于医疗用途的组合物和包含金属标记的肽的用于医疗用途的制剂
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申请号： US10591252申请日： 2005-03-23
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公开(公告)号： US07854918B2公开(公告)日： 2010-12-21
- 发明人: Takayoshi Kawaguchi , Ikuya Seki , Marino Maemura
- 申请人： Takayoshi Kawaguchi , Ikuya Seki , Marino Maemura
- 申请人地址： JP Tokyo
- 专利权人： Nihon Medi-Physics Co., Ltd.
- 当前专利权人： Nihon Medi-Physics Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 代理机构： Sughrue Mion, PLLC
- 优先权： JP2004-089620 20040325
- 国际申请： PCT/JP2005/005182 WO 20050323
- 国际公布： WO2005/092396 WO 20051006
- 主分类号： A61K51/00
- IPC分类号： A61K51/00 ; A61M36/14
摘要：
By preliminarily dissolving a basic organic compound in an aqueous solvent in which a peptide usable in metal-labeling is to be dissolved, the solubility of the peptide is improved and thus metal-labeling can be carried out without heating. A composition for medical use containing a peptide usable in metal-labeling and a basic organic compound acceptable as a pharmaceutical additive can be utilized as a preparation useful in image diagnosis, radiotherapy and so on.
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