发明授权
- 专利标题： F11 receptor (F11R) antagonists as therapeutic agents
- 专利标题（中）： F11受体（F11R）拮抗剂作为治疗剂
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申请号： US12141635申请日： 2008-06-18
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公开(公告)号： US07829663B2公开(公告)日： 2010-11-09
- 发明人: Elizabeth Kornecki , Anna Babinska , Yigal H. Ehrlich
- 申请人： Elizabeth Kornecki , Anna Babinska , Yigal H. Ehrlich
- 代理机构： Scully, Scott, Murphy & Presser, P.C.
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K38/16 ; A61K38/10 ; A61K39/00
摘要：
The present invention provides a cell adhesion molecule (CAM), designated F11 receptor (F11R), which is a member of the immunoglobulin super family localized on the surface of human platelets, and determined to effect platelet aggregation, secretion, platelet spreading and cellular adhesion. Cloned F11R cDNA and full length F11R cDNA and amino acid sequences are provided. F11R-antagonists and methods for the prevention and treatment of thrombosis, atherosclerosis, heart attacks, stroke and other clinical disorders involving thrombus formation are also provided.
公开/授权文献
- US20090170779A1 F11 Receptor (F11R) Antagonists as Therapeutic Agents 公开/授权日：2009-07-02
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