发明授权
- 专利标题： Fused ring dicationic anti-protozoan agents and their prodrugs
- 专利标题（中）： 融合环双阳离子抗原生动物及其前药
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申请号： US10992607申请日： 2004-11-18
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公开(公告)号： US07825279B2公开(公告)日： 2010-11-02
- 发明人: David W. Boykin , Richard R. Tidwell , W. David Wilson , Reto Brun , Reem K. Arafa , Chad E. Stephens
- 申请人： David W. Boykin , Richard R. Tidwell , W. David Wilson , Reto Brun , Reem K. Arafa , Chad E. Stephens
- 申请人地址： US NC Chapel Hill US GA Atlanta
- 专利权人： The University of North Carolina at Chapel Hill,Georgia State University Research Foundation, Inc.
- 当前专利权人： The University of North Carolina at Chapel Hill,Georgia State University Research Foundation, Inc.
- 当前专利权人地址： US NC Chapel Hill US GA Atlanta
- 代理机构： Jenkins, Wilson, Taylor & Hunt, P.A.
- 主分类号： C07C279/18
- IPC分类号： C07C279/18 ; C07D219/12 ; C07D213/06 ; A61K31/155 ; A61K31/235 ; A61K31/24 ; A61K31/44
摘要：
Novel fused ring dicationic anti-protozoan compounds. Representative protozoan species include but are not limited to Trypanosoma brucei rhodesiense (T.b.r.) and Plasmodium falciparum. Prodrugs of these compounds can be used as an oral treatment for malaria and human African trypanosomiasis.
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