发明授权
US07799820B2 2-Heterocycle-substituted indole derivatives for treating diabetes and associated conditions
有权
用于治疗糖尿病和相关病症的2-杂环取代的吲哚衍生物
- 专利标题： 2-Heterocycle-substituted indole derivatives for treating diabetes and associated conditions
- 专利标题（中）： 用于治疗糖尿病和相关病症的2-杂环取代的吲哚衍生物
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申请号： US11992555申请日： 2006-09-29
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公开(公告)号： US07799820B2公开(公告)日： 2010-09-21
- 发明人: Keiji Takahashi , Yoshio Ogino , Teruyuki Nishimura
- 申请人： Keiji Takahashi , Yoshio Ogino , Teruyuki Nishimura
- 申请人地址： JP Tokyo
- 专利权人： Banyu Pharmaceutical Co., Ltd.
- 当前专利权人： Banyu Pharmaceutical Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 代理商 Richard C. Billups; John C. Todaro
- 优先权： JP2005-288399 20050930
- 国际申请： PCT/JP2006/320010 WO 20060929
- 国际公布： WO2007/037534 WO 20070405
- 主分类号： A61K31/405
- IPC分类号： A61K31/405
摘要：
Disclosed is a compound represented by the formula (I) below, which has a glucokinase-activating effect and is thus useful for treatment of diabetes or obesity, or a pharmaceutically acceptable salt thereof. In the formula, R1 represents an aryl or the like; R11 represents an aryl or the like; R2 represents a formyl or the like, R3 represents a C1-6 alkyl or the like; R3 represents a hydrogen atom or the like; Z1 represents —O— or the like; Z2 represents —O— or the like; Y1-Y4 respectively represent a carbon atom or a nitrogen atom; ring A represents a heteroaryl group; X represents a carbon atom or the like; m represents an integer of 0-2; and q represents an integer of 0-2.
公开/授权文献
- US20090118304A1 2-HETEROARYL-SUBSTITUTED INDOLE DERIVATIVE 公开/授权日：2009-05-07
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