Invention Grant
- Patent Title: Expression and use of anti-CD20 Antibodies
- Patent Title (中): 抗CD20抗体的表达和使用
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Application No.: US10238681Application Date: 2002-09-11
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Publication No.: US07744877B2Publication Date: 2010-06-29
- Inventor: Darrell R. Anderson , Nabil Hanna , John E. Leonard , Roland A. Newman , Mitchell E. Reff , William H. Rastetter
- Applicant: Darrell R. Anderson , Nabil Hanna , John E. Leonard , Roland A. Newman , Mitchell E. Reff , William H. Rastetter
- Applicant Address: US MA Cambridge
- Assignee: Biogen Idec Inc.
- Current Assignee: Biogen Idec Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Sidley Austin LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C07K16/30

Abstract:
Disclosed herein are methods of depleting peripheral blood B cells in a human host comprising administering to the host an immunologically active anti-CD20 antibody in an amount effective to deplete peripheral blood B cells in the host.
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