发明授权
- 专利标题： Pyrrolidinone glucokinase activators
- 专利标题（中）： 吡咯烷酮葡糖激酶激活剂
-
申请号： US12400065申请日： 2009-03-09
-
公开(公告)号： US07741327B2公开(公告)日： 2010-06-22
- 发明人: Steven Joseph Berthel , John A Brinkman , Stuart Hayden , Nancy-Ellen Haynes , Robert Francis Kester , Lee Apostle McDermott , Yimin Qian , Ramakanth Sarabu , Nathan Robert Scott , Jefferson Wright Tilley
- 申请人： Steven Joseph Berthel , John A Brinkman , Stuart Hayden , Nancy-Ellen Haynes , Robert Francis Kester , Lee Apostle McDermott , Yimin Qian , Ramakanth Sarabu , Nathan Robert Scott , Jefferson Wright Tilley
- 申请人地址： US NJ Nutley
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 代理商 George W. Johnston; Dennis P. Tramaloni; Samuel H. Megerditchian
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; A61K31/4439 ; A61K31/433 ; A61K31/428 ; A61K31/426 ; A61K31/423 ; A61K31/421 ; A61K31/4155 ; C07D403/12 ; C07D401/12 ; C07D285/08 ; C07D277/82 ; C07D277/38 ; C07D263/54 ; C07D263/48 ; C07D231/56 ; C07D231/38
摘要：
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
公开/授权文献
- US20090264445A1 PYRROLIDINONE GLUCOKINASE ACTIVATORS 公开/授权日：2009-10-22
信息查询
IPC分类:
