Invention Grant
US07718414B2 Microorganism of Enterobacteriacae genus haboring genes associated with L-carnitine biosynthesis and method of producing L-carnitine using the microorganism
有权
具有与L-肉碱生物合成相关的基因的肠杆菌属的微生物和使用微生物生产L-肉毒碱的方法
- Patent Title: Microorganism of Enterobacteriacae genus haboring genes associated with L-carnitine biosynthesis and method of producing L-carnitine using the microorganism
- Patent Title (中): 具有与L-肉碱生物合成相关的基因的肠杆菌属的微生物和使用微生物生产L-肉毒碱的方法
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Application No.: US11994969Application Date: 2006-07-07
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Publication No.: US07718414B2Publication Date: 2010-05-18
- Inventor: Whan-Koo Kang , Bheong-Uk Lee , Young-Hoon Park , Eun-Sung Koh , Jae-Yeong Ju , Jin-Ho Lee , Hye-Won Kim , Hye-Jin Choi
- Applicant: Whan-Koo Kang , Bheong-Uk Lee , Young-Hoon Park , Eun-Sung Koh , Jae-Yeong Ju , Jin-Ho Lee , Hye-Won Kim , Hye-Jin Choi
- Applicant Address: KR
- Assignee: CJ Cheiljedang Corp.
- Current Assignee: CJ Cheiljedang Corp.
- Current Assignee Address: KR
- Agency: Cantor Colburn LLP
- Priority: KR10-2005-0061142 20050707
- International Application: PCT/KR2006/002661 WO 20060707
- International Announcement: WO2007/007987 WO 20070118
- Main IPC: C12P13/00
- IPC: C12P13/00 ; C12N1/20
Abstract:
Provided is a microorganism that belongs to Enterobacteriacae and a method of producing L-carnitine using the same. The microorganism includes polynucleotide encoding activity of S-adenosylmethionine-6-N-iysine methyltransferase from Neurospora crassa, polynucleotide encoding activity of 6-N-trimethyllysine hydroxylase, polynucleotide encoding activity of 3-hydroxy-6-N-trimethyllysine aldolase, and polynucleotide encoding activity of γ-trimethylaminoaldehyde dehydrogenase and y-butyrobetaine hydroxylase.
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