发明授权
US07645769B2 Inhibitors of c-Jun N-terminal kinases for the treatment of neurodegenerative disorders relating to apoptosis and/or inflammation
有权
用于治疗与凋亡和/或炎症相关的神经变性疾病的c-Jun N-末端激酶抑制剂
- 专利标题: Inhibitors of c-Jun N-terminal kinases for the treatment of neurodegenerative disorders relating to apoptosis and/or inflammation
- 专利标题(中): 用于治疗与凋亡和/或炎症相关的神经变性疾病的c-Jun N-末端激酶抑制剂
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申请号: US11499334申请日: 2006-08-04
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公开(公告)号: US07645769B2公开(公告)日: 2010-01-12
- 发明人: Afzal Khan , Darren Peter Medland , Gurpreet Singh Bhatia
- 申请人: Afzal Khan , Darren Peter Medland , Gurpreet Singh Bhatia
- 申请人地址: JP
- 专利权人: Eisai R & D Management Co., Ltd.
- 当前专利权人: Eisai R & D Management Co., Ltd.
- 当前专利权人地址: JP
- 代理机构: Wilmer Cutler Pickering Hale & Dorr LLP.
- 优先权: GB0516156.7 20050805
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; A61K31/4375
摘要:
The present invention provides novel compounds of formula I and their use in the inhibition of c-Jun N-terminal kinases. The present invention further provides the use of these compounds in medicine, in particular in the prevention and/or treatment of neurodegenerative disorders related to apoptosis and/or inflammation.
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