Invention Grant
US07622537B2 Methods for manufacturing amino acid mimetic copolymers and use of same
失效
制备氨基酸模拟共聚物的方法及其用途
- Patent Title: Methods for manufacturing amino acid mimetic copolymers and use of same
- Patent Title (中): 制备氨基酸模拟共聚物的方法及其用途
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Application No.: US11942696Application Date: 2007-11-19
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Publication No.: US07622537B2Publication Date: 2009-11-24
- Inventor: Stephen Pacetti
- Applicant: Stephen Pacetti
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agency: Squire Sanders & Dempsey LLP
- Main IPC: C08F220/48
- IPC: C08F220/48 ; C08F220/06 ; C08F118/02 ; C08F20/70

Abstract:
Biocompatible polymers are manufactured to include an amino acid mimetic monomer and one or more hydrophobic acrylate monomers. The amino acid mimetic monomers are selected to mimic the side chain of the amino acids asparagine or glutamine. The amino acid mimetic monomer can be a methacryloyl or acryloyl derivative of 2-hydroxyacetamide, 3-hydroxypropionamide, alaninamide, lactamide, or glycinamide. These amide functional groups offer the advantage of moderate hydrophilicity with little chemical reactivity. The amino acid mimetic monomer can be copolymerized with one or more hydrophobic acrylate monomers to obtain desired coating properties.
Public/Granted literature
- US20080124450A1 METHODS FOR MANUFACTURING AMINO ACID MIMETIC COPOLYMERS AND USE OF SAME Public/Granted day:2008-05-29
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