Invention Grant
- Patent Title: Mitotic kinesin inhibitors
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Application No.: US11630224Application Date: 2005-06-27
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Publication No.: US07618971B2Publication Date: 2009-11-17
- Inventor: Paul J. Coleman , Christopher D. Cox , Mark E. Fraley , George D. Hartman , John Schreier
- Applicant: Paul J. Coleman , Christopher D. Cox , Mark E. Fraley , George D. Hartman , John Schreier
- Applicant Address: US NJ Rahway
- Assignee: Merck & Co. Inc.
- Current Assignee: Merck & Co. Inc.
- Current Assignee Address: US NJ Rahway
- Agent Nicole M. Beeler; David A. Muthard
- International Application: PCT/US2005/022877 WO 20050627
- International Announcement: WO2006/007496 WO 20060119
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/4196 ; A61K31/4155 ; C07D403/06 ; C07D249/08 ; C07D231/06
Abstract:
The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
Public/Granted literature
- US20080027058A1 Mitotic Kinesin Inhibitors Public/Granted day:2008-01-31
Information query
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