发明授权
US07595147B2 Methods to identify agents that bind the flap-tip helix of RNA polymerase
有权
鉴定结合RNA聚合酶襟翼尖端螺旋的试剂的方法
- 专利标题: Methods to identify agents that bind the flap-tip helix of RNA polymerase
- 专利标题(中): 鉴定结合RNA聚合酶襟翼尖端螺旋的试剂的方法
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申请号: US10128151申请日: 2002-04-23
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公开(公告)号: US07595147B2公开(公告)日: 2009-09-29
- 发明人: Robert C. Landick , Katherine M. Geszvain , Irina E. Artsimovitch , Innokenti I. Toulokhonov , Rachel A. Mooney
- 申请人: Robert C. Landick , Katherine M. Geszvain , Irina E. Artsimovitch , Innokenti I. Toulokhonov , Rachel A. Mooney
- 申请人地址: US WI Madison
- 专利权人: Wisconsin Alumni Research Foundation
- 当前专利权人: Wisconsin Alumni Research Foundation
- 当前专利权人地址: US WI Madison
- 代理机构: Schwegman, Lundberg & Woessner, P.A.
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; G01N33/55
摘要:
The invention provides methods to identify moieties which specifically bind the flap-tip helix of the β subunit of RNA polymerase and to identify inhibitors of the interaction between those moieties and the flap-tip helix.
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