发明授权
- 专利标题： Tyrosine kinase inhibitors
- 专利标题（中）： 酪氨酸激酶抑制剂
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申请号： US11473273申请日： 2006-06-22
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公开(公告)号： US07550478B2公开(公告)日： 2009-06-23
- 发明人: Christopher J. Dinsmore , Ana Esther Gabarda Ortega , David J. Guerin , James P. Jewell , Jason D. Katz , Jongwon Lim , Michelle R. Machacek , Ryan D. Otte , Jonathan R. Young
- 申请人： Christopher J. Dinsmore , Ana Esther Gabarda Ortega , David J. Guerin , James P. Jewell , Jason D. Katz , Jongwon Lim , Michelle R. Machacek , Ryan D. Otte , Jonathan R. Young
- 申请人地址： US NJ Rahway
- 专利权人： Merck & Co. Inc.
- 当前专利权人： Merck & Co. Inc.
- 当前专利权人地址： US NJ Rahway
- 代理商 David A. Muthard
- 主分类号： A01N43/42
- IPC分类号： A01N43/42 ; A61K31/44 ; C07D221/00
摘要：
The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine compounds, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
公开/授权文献
- US20060293358A1 Tyrosine kinase inhibitors 公开/授权日：2006-12-28
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