发明授权
- 专利标题: Cyclic aminophenyl sulfamate derivative
- 专利标题(中): 环氨基苯基氨基磺酸酯衍生物
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申请号: US10558253申请日: 2004-05-07
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公开(公告)号: US07449466B2公开(公告)日: 2008-11-11
- 发明人: Shigehiro Takegawa , Shigeki Iwashita , Makoto Okada , Takayoshi Nakagawa , Naoyuki Koizumi , Tomohito Fujii
- 申请人: Shigehiro Takegawa , Shigeki Iwashita , Makoto Okada , Takayoshi Nakagawa , Naoyuki Koizumi , Tomohito Fujii
- 申请人地址: JP Tokyo
- 专利权人: Aska Pharmaceutical Co., Ltd.
- 当前专利权人: Aska Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: JP2003-143503 20030521
- 国际申请: PCT/JP2004/006490 WO 20040507
- 国际公布: WO2004/103971 WO 20041202
- 主分类号: A61K31/497
- IPC分类号: A61K31/497 ; A61K31/4965 ; A61K31/445 ; A01N43/40 ; C07D401/00 ; C07D241/04 ; C07D295/00 ; C07D211/40 ; C07D211/54
摘要:
This invention provides cyclicamino-phenyl sulfamate derivatives represented by a formula wherein each of R1 and R2 stands for hydrogen or lower alkyl; each of R3 and R4 stands for hydrogen, halogen, cyano or the like; A stands for nitrogen or CH; B stands for CH2, SO2, CO, optionally substituted phenyl or the like; and R5 stands for alkyl, phenyl, amino or the like, or salts thereof which exhibit excellent steroid sulfatase inhibitory activity and are useful for prevention or treatment of diseases associated with steroids such as estrogen, androgen and the like.
公开/授权文献
- US20060189625A1 Cyclic aminophenyl sulfamate derivative 公开/授权日:2006-08-24
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