发明授权
US07332576B2 Biosynthetic gene cluster for ambruticins and the encoded proteins
有权
氨基丁酸和编码蛋白的生物合成基因簇
- 专利标题: Biosynthetic gene cluster for ambruticins and the encoded proteins
- 专利标题(中): 氨基丁酸和编码蛋白的生物合成基因簇
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申请号: US11075185申请日: 2005-03-07
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公开(公告)号: US07332576B2公开(公告)日: 2008-02-19
- 发明人: Christopher D. Reeves , Bryan Julien , Ralph C. Reid
- 申请人: Christopher D. Reeves , Bryan Julien , Ralph C. Reid
- 申请人地址: US CA Hayward
- 专利权人: Kosan Biosciences Inc.
- 当前专利权人: Kosan Biosciences Inc.
- 当前专利权人地址: US CA Hayward
- 代理商 Gary W. Ashley
- 主分类号: C07K1/00
- IPC分类号: C07K1/00
摘要:
Domains of ambruticin polyketide synthase and modification enzymes and polynucleotides encoding them are provided. Methods to prepare ambruticin in pharmaceutically useful quantities are described, as are methods to prepare ambruticin analogs and other polyketides using the polynucleotides encoding ambruticin synthase domains or modifying enzymes.
公开/授权文献
- US20050266434A1 Biosynthetic gene cluster for ambruticins 公开/授权日:2005-12-01
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