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US07332576B2 Biosynthetic gene cluster for ambruticins and the encoded proteins 有权
氨基丁酸和编码蛋白的生物合成基因簇

Biosynthetic gene cluster for ambruticins and the encoded proteins
摘要:
Domains of ambruticin polyketide synthase and modification enzymes and polynucleotides encoding them are provided. Methods to prepare ambruticin in pharmaceutically useful quantities are described, as are methods to prepare ambruticin analogs and other polyketides using the polynucleotides encoding ambruticin synthase domains or modifying enzymes.
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