Invention Grant
US07262215B2 N-carbacycle monosubstituted indolocarbazoles as protein kinase inhibitors
失效
N-半胱氨酸单取代的吲哚卡巴唑作为蛋白激酶抑制剂
- Patent Title: N-carbacycle monosubstituted indolocarbazoles as protein kinase inhibitors
- Patent Title (中): N-半胱氨酸单取代的吲哚卡巴唑作为蛋白激酶抑制剂
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Application No.: US10496505Application Date: 2002-12-04
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Publication No.: US07262215B2Publication Date: 2007-08-28
- Inventor: Heidi Sahagun-Krause , Olivier Thillaye Du Boullay , Valerie Thillaye Du Boullay , Laura Casiraghi , Hans-Wolfgang Klafki , Pierfausto Seneci , Tobias Braxmeier , Silvia Müller , Wolfgang Fr{hacek over (o)}hner , Barbara Monse , Sandra Gordon , Hanno M. Roder
- Applicant: Heidi Sahagun-Krause , Olivier Thillaye Du Boullay , Valerie Thillaye Du Boullay , Laura Casiraghi , Hans-Wolfgang Klafki , Pierfausto Seneci , Tobias Braxmeier , Silvia Müller , Wolfgang Fr{hacek over (o)}hner , Barbara Monse , Sandra Gordon , Hanno M. Roder
- Applicant Address: DE Munich
- Assignee: NAD AG
- Current Assignee: NAD AG
- Current Assignee Address: DE Munich
- Agency: McAndrews, Held & Malloy, Ltd.
- Priority: DE10161940 20011217
- International Application: PCT/EP02/13753 WO 20021204
- International Announcement: WO03/051887 WO 20030626
- Main IPC: A61K31/4035
- IPC: A61K31/4035 ; A61K31/5377 ; A61K31/4192 ; A61K31/407 ; C07D249/04 ; C07D413/14 ; C07D487/14 ; C09B5/26
Abstract:
This invention relates to N-carbacycle monosubstituted indolocarbazole compounds. Furthermore, this invention relates to medicaments comprising N-carbacycle monosubstituted indolocarbazoles compounds and the use of such compounds for treating non-insulin dependent diabetes mellitus, acute stroke and other neurotraumatic injuries, for treating diabetes mellitus, as a chemotherapeutic for the treatment of various malignant diseases, for treating diseases caused by malfunctioning of specific signaling pathways, and for treating neurodegenerative diseases such as for example Alzheimer's disease.
Public/Granted literature
- US20050075386A1 N-carbacycle monosubstituted indolocarbazoles as protein kinase inhibitors Public/Granted day:2005-04-07
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